Complement in neuroprotection and neurodegeneration
Acute neurodegeneration is associated with high morbidity and mortality, and there are few effective treatments. Inflammation is central to the process of neuronal death, yet the roles of the complement cascade in this process have proven to be complex and hard to unravel.
Cerebral Intraparenchymal Hemorrhage: A Review, JAMA 2019
Importance Although spontaneous intraparenchymal hemorrhage (IPH) accounts for less than 20% of cases of stroke, it continues to be associated with the highest mortality of all forms of stroke and substantial morbidity rates.
Apoptosis and Caspasesin Neurodegenerative Diseases
Acute and chronic neurodegenerative diseases are illnesses
associated with high morbidity and mortality, and few or no effective options
are available for their treatment.