Inhibition of mitochondrial protein import by mutant huntingtin

Chiari malformation, an anomaly of the posterior cranial
fossa, also known as Arnold–Chiari malformation, was described in autopsies
by Hans Chiari, an Austrian pathologist, in 1891. He defined four
distinct anatomical configurations in which the cerebellar tonsils (the most caudal
part of the cerebellum) protruded below the lower margin of the foramen magnum.1

Congenital and Acquired Chiari Syndrome

Chiari malformation, an anomaly of the posterior cranial
fossa, also known as Arnold–Chiari malformation, was described in autopsies
by Hans Chiari, an Austrian pathologist, in 1891. He defined four
distinct anatomical configurations in which the cerebellar tonsils (the most caudal
part of the cerebellum) protruded below the lower margin of the foramen magnum.1